Oocyte Donation: An Overview

  • Home / Oocyte Donation: An Overview

Oocyte Donation: An Overview

*Nalini Mahajan

Mother and Child Hospital, New Delhi, India
*Correspondence to dr.nalinimahajan@gmail.com

Disclosure: The author has declared no conflicts of interest.
Received: 03.04.17 Accepted: 11.07.17
Citation: EMJ Repro Health. 2017;3[1]:68-74.


The use of donor oocytes has expanded the scope of assisted reproductive technology (ART) for women with poor oocyte quantity and quality. In vitro fertilisation with oocyte donation (IVF-OD) is considered to give better implantation, pregnancy, and livebirth rates compared to IVF with autologous oocytes. Maternal age, infertility factors, BMI, smoker status, and ethnicity reduce reproductive outcome. An increasing demand and a good success rate with oocyte vitrification programmes have led to the formation of oocyte banks, reducing the need for donor–recipient cycle synchronisation and allowing egg sharing. Obstetric and neonatal complications with donor oocytes are significantly increased in comparison to autologous IVF and spontaneous pregnancies. The risk of pregnancy-induced hypertension (PIH), pre-eclampsia (PE), prematurity, low birth weight and very low birth weight are increased, as is the need for operative delivery. The age group of these patients and the increase in obstetric and neonatal complications associated with multiple pregnancy, dictates the use of single embryo transfer. As increasingly older women enter these programmes, concerns for maternal and fetal health necessitate guidelines to set an age limit for offering the procedure. Advanced paternal age is also raising concerns in long-term follow-up studies in neonates.

The post Oocyte Donation: An Overview appeared first on European Medical Journal.

About Post Author

Medical CPD & News

The Digitalis CPD trawler searches the web for all the latest news and journals.

Privacy Preference Center

Close your account?

Your account will be closed and all data will be permanently deleted and cannot be recovered. Are you sure?

Are you sure?

By disagreeing you will no longer have access to our site and will be logged out.